ROS-ERS inducer 2

• Description:

  ROS-ERS inducer 2 (Complex 3f) triggers intracellular ROS generation and affect the function of mitochondria. promote the release of damage-associated molecular patterns (DAMPs), induce immunogenic cell death (ICD) and activates endoplasmic reticulum stress (ERS) . ROS-ERS inducer 2 plays an important role in anti-liver cancer research[1].

• UNSPSC:

  12352005

• Target:

  Reactive Oxygen Species (ROS)

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  FC1=CC=C(C2=C(N(CC)[C-2](N2CC)=[Pt+4]([Br-])([N]3=CC=CC=C3)[Cl-])C4=CC=C(C=C4)F)C=C1

• Molecular Formula:

  C24H23BrClF2N3Pt

• Molecular Weight:

  701.90

• References & Citations:

  [1]Lu Tang, et al. More than just DNA damage: Pt (ΙΙ) -NHC complexes derived from 4,5-diarylimidazoles augment immunogenic cell death. Eur J Med Chem. 2025 Jan 15:282:117014.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3081736-89-9]