ROS-ERS inducer 1

CAT: 0931-T74225-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T74225-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Reactive Oxygen Species, Others

Related Pathways

NF-κB, Others, Metabolism, Immunology/Inflammation

Bioactivity

ROS-ERS inducer 1, a type II immunogenic cell death (ICD) inducer, is a Pt (II) -N-heterocyclic carbene (Pt (II) -NHC) complex derived from 4,5-diarylimidazole. It induces endoplasmic reticulum stress (ERS) along with reactive oxygen species (ROS) generation, leading to the release of damage-associated molecular patterns (DAMPs) in HCC cells, showcasing significantly higher anticancer activities than Cisplatin [1].

Molecular Formula

C24H23F2I2N3Pt

Molecular Weight

840.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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