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ROS-IN-2

CAT: 0804-HY-149586Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-149586Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ROS-IN-2 (compound 85) is a seco-lupane triterpenoid derivative. ROS-IN-2 blocks ROS production and protects mitochondria from damage by inhibiting excessive production of oxidative stressors. ROS-IN-2 can be used for myocardial ischemia/reperfusion (MI/R) injury research[1].
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ros-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(OCCC)CC1[C@]2(C)[C@]3([H])[C@@]([C@@](CC[C@]4(C(NCCOCCOC(C5=CC(Cl)=CS5)=O)=O)[C@]6([H])[C@H](C(C)=C)CC4)(C)[C@]6([H])C[C@H]3O)(C)CCC2C(C)(C)O1
Molecular Formula
C42H62ClNO8S
Molecular Weight
776.46
References & Citations
[1]Teng H, et al. Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-1α axis. Biomed Pharmacother. 2023 Nov;167:115452.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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