ROS inducer 8

CAT: 0931-T205358-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205358-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ROS|||Reactive Oxygen Species|||Antibacterial
Related Pathways
Microbiology/Virology|||NF-?B|||Metabolism|||Immunology/Inflammation
Bioactivity
ROS inducer 8 (Compound 11g) acts as an inhibitor of glutathione (GSH) and promotes the accumulation of reactive oxygen species (ROS) in Enterococcus faecalis, exhibiting antibacterial properties. It is capable of disrupting biofilms and inhibiting S. aureus and E. faecalis with minimum inhibitory concentrations (MICs) of 8 ?g/mL and 2 ?g/mL, respectively, demonstrating a post-antibiotic effect. Additionally, ROS inducer 8 shows low hemolytic toxicity on sheep red blood cells with an HC50 greater than 1280 ?g/mL.
Molecular Formula
C26H31FN6O6
Molecular Weight
542.56
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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