CDK8-IN-17

• Description :

  CDK8-IN-17 (Compound WS-2) is a CDK8 inhibitor with an IC50 value of 9 nM, which can be used in cancer research[1].

• CAS Number :

  [451458-32-5]

• UNSPSC :

  12352005

• Target :

  CDK

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Cancer

• Smiles :

  O=C1C2=C(N=C(N1C3=CC=C(CC)C=C3)SCC4=C(C)C=CC=C4)NN=C2

• Molecular Formula :

  C21H20N4OS

• Molecular Weight :

  376.47

• References & Citations :

  [1]Wang T, et al. Discovery of novel CDK8 inhibitors using multiple crystal structures in docking-based virtual screening[J]. European journal of medicinal chemistry, 2017, 129: 275-286.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  CDK8