CDK8-IN-17

• Description:

  CDK8-IN-17 (Compound WS-2) is a CDK8 inhibitor with an IC50 value of 9 nM, which can be used in cancer research[1].

• UNSPSC:

  12352005

• Target:

  CDK

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Smiles:

  O=C1C2=C(N=C(N1C3=CC=C(CC)C=C3)SCC4=C(C)C=CC=C4)NN=C2

• Molecular Formula:

  C21H20N4OS

• Molecular Weight:

  376.47

• References & Citations:

  [1]Wang T, et al. Discovery of novel CDK8 inhibitors using multiple crystal structures in docking-based virtual screening[J]. European journal of medicinal chemistry, 2017, 129: 275-286.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CDK8

• CAS Number:

  [451458-32-5]