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P38α-MK2-IN-1

CAT: 0804-HY-168841Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168841Size:1 Each
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Description
P38α-MK2-IN-1 (Compound 36) is a p38α-MK2 complex inhibitor (IC50: 5 nM) . p38α-MK2-IN-1 has a robust inflammation inhibitory effect and joint repair ability[1].
CAS Number
3031770-03-0
UNSPSC
12352101
Target
MAPKAPK2 (MK2) ; p38 MAPK
Related Pathways
MAPK/ERK Pathway
Field of Research
Inflammation/Immunology
Smiles
O=C1C(C)=C(O[C@@H](C)C2=NC=C(F)C=C2F)C=C(C)N1C3=C(C)C=NC(C4=NC(C(O)(C)C)=NC=C4)=C3F
Molecular Formula
C27H26F3N5O3
Molecular Weight
525.52
References & Citations
[1]Fu D, et al. Discovery of a Novel p38α-MK2 Complex Inhibitor as a Potential Choice for Autoimmune Diseases. J Med Chem. 2025 Jan 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P38α

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Alternative Products

CatalogName
T204655-01P38α-MK2-IN-1
T36778-01MK2-IN-1
T4442-01MK2-IN-1 hydrochloride
MBS131203-01MK2-IN-1 HCl
A21662-25MK2-IN-1 hydrochloride 25mg
A21662-100MK2-IN-1 hydrochloride 100mg
A21662-5MK2-IN-1 hydrochloride 5mg
A21662-200MK2-IN-1 hydrochloride 200mg
A21662-50MK2-IN-1 hydrochloride 50mg
A21662-10MK2-IN-1 hydrochloride 10mg

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