FTO-IN-13

• Description :

  FTO-IN-13 (compound 8t) is a potent FTO inhibitor. FTO-IN-13 shows antiproliferative activity. FTO-IN-13 induces apoptosis. FTO-IN-13 decreases the protein expression of Bcl-2 and Caspase 3 active. FTO-IN-13 decreases MYC and CEBPA gene expression. FTO-IN-13 shows anticancer activity[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Fat Mass and Obesity-associated Protein (FTO)

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  O=C(C1=CC2=C(C=C1O)C=CC=C2)N/N=C/C3=CC(Br)=C(C(Br)=C3O)O

• Molecular Formula :

  C18H12Br2N2O4

• Molecular Weight :

  480.11

• References & Citations :

  [1]Liang X, et al. Discovery of Novel RNA Demethylase FTO Inhibitors Featuring an Acylhydrazone Scaffold with Potent Antileukemia Activity. J Med Chem. 2025 Jan 16.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [687600-25-5]