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Squalamine (phosphate)

CAT: 0804-HY-16468ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-16468ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Squalamine phosphate (Compound ENT-01) is an orally active neuroprotective agent. Squalamine phosphate can displace α-Syn that is bound electrostatically to nerve cell membranes and prevent aggregation of α-Syn. Squalamine phosphate can be used for the research of neurological disease, such as Parkinson’s disease[1].
CAS Number
[1309370-82-8]
Product Name Alternative
ENT 01; MSI-1256 (phosphate)
UNSPSC
12352211
Target
α-synuclein
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=P(O)(O)O.O[C@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CC[C@H](C(C)C)OS(=O)(O)=O)C)([H])[C@@]4([C@@](C[C@H](CC4)NCCCNCCCCN)([H])C1)C
Molecular Formula
C34H68N3O9PS
Molecular Weight
725.96
References & Citations
[1]Camilleri M, et al. Oral ENT-01 Targets Enteric Neurons to Treat Constipation in Parkinson Disease : A Randomized Controlled Trial. Ann Intern Med. 2022 Dec;175 (12) :1666-1674.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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