BWC0977 (formic)

• Description :

  BWC0977 formic is an antibacterial agent that inhibits bacterial DNA replication via inhibition of DNA gyrase and topoisomerase IV. BWC0977 formic exhibits a minimum inhibitory concentration (MIC90) of 0.03-2 µg/mL against MDR (Multi-Drug Resistant) Gram-negative bacteria[1].

• UNSPSC :

  12352005

• Target :

  Bacterial; DNA/RNA Synthesis; Topoisomerase

• Related Pathways :

  Anti-infection; Cell Cycle/DNA Damage

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Purity :

  98.91

• Smiles :

  O=C1N(C)C2=C(CCNC[C@H]3CN(C4=CN=C(OCC(N5)=O)C5=N4)C(O3)=O)C(F)=CC=C2C=C1.OC=O

• Molecular Formula :

  C23H23FN6O7

• Molecular Weight :

  514.46

• References & Citations :

  [1]Shahul Hameed P, et al. BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections. Clinical Trial Nat Commun. 2024 Sep 18;15 (1) :8202.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Topoisomerase

• CAS Number :

  [3027162-72-4]