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BWC0977

CAT: 0804-HY-162959Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162959Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BWC0977 is an antibacterial agent that inhibits bacterial DNA replication via inhibition of DNA gyrase and topoisomerase IV. BWC0977 exhibits a minimum inhibitory concentration (MIC90) of 0.03-2 µg/mL against MDR (Multi-Drug Resistant) Gram-negative bacteria[1].
CAS Number
2254567-00-3
UNSPSC
12352101
Target
Bacterial; DNA/RNA Synthesis; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bwc0977.html
Smiles
O=C1N(C)C2=C(CCNC[C@H]3CN(C4=CN=C(OCC(N5)=O)C5=N4)C(O3)=O)C(F)=CC=C2C=C1
Molecular Formula
C22H21FN6O5
Molecular Weight
468.44
References & Citations
[1]Shahul Hameed P, et al. BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections. Clinical Trial Nat Commun. 2024 Sep 18;15 (1) :8202.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
Topoisomerase

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