PF-670462

• Description:

  PF-670462 is a selective CKI ε/δ inhibitor. PF-670462 effectively regulates the phase of the circadian rhythm[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Casein Kinase

• Related Pathways:

  Cell Cycle/DNA Damage; Stem Cell/Wnt

• Field of Research:

  Neurological Disease

• Smiles:

  NC1=NC=CC(C2=C(C3=CC=C(F)C=C3)N=CN2C4CCCCC4)=N1

• Molecular Formula:

  C19H20FN5

• Molecular Weight:

  337.39

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

• References & Citations:

  [1]Sprouse J, et al. Chronic treatment with a selective inhibitor of casein kinase I delta/epsilon yields cumulative phase delays in circadian rhythms. Psychopharmacology (Berl) . 2010 Jul;210 (4) :569-76.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  CK1

• CAS Number:

  [950980-98-0]