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(S) -Hydroxychloroquine (sulfate)

CAT: 0804-HY-145530-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-145530-01Size:500 µg
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Description
(S) -Hydroxychloroquine ((S) -HCQ) sulfate is an isomer of Hydroxychloroquine. (S) -Hydroxychloroquine sulfate (2.5-20 mg/mL) reduces the rate of insulin degradation in liver homogenates isolated from non-diabetic and diabetic rats. Formulations containing Hydroxychloroquine have been used in the study of malaria, rheumatoid arthritis, and systemic lupus erythematosus[1].
CAS Number
155204-09-4
Product Name Alternative
(S) -HCQ (sulfate)
UNSPSC
12352005
Hazard Statement
H302-H315-H317-H319-H334-H335
Target
Autophagy; Drug Isomer; Parasite; SARS-CoV; Toll-like Receptor (TLR)
Related Pathways
Anti-infection; Autophagy; Immunology/Inflammation; Others
Field of Research
Infection; Metabolic Disease; Inflammation/Immunology
Smiles
O=S(O)(O)=O.OCCN(CC)CCC[C@H](C)NC1=CC=NC2=C1C=CC(Cl)=C2
Molecular Formula
C18H28ClN3O5S
Molecular Weight
433.95
Precautions
P261-P264-P270-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Emami J, et al. Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic rats. Life Sci. 1999;64 (5) :325-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported