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(9R) -RO7185876

CAT: 0931-T204358-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204358-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2226077-86-5
Target
Gamma-secretase, Beta Amyloid
Related Pathways
Stem Cells, Proteases/Proteasome, Neuroscience
Bioactivity
(9R) -RO7185876 (Compound example 16) is a γ-secretase inhibitor. It reduces the secretion of Αβ42. This compound can be employed in the research of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, multi-infarct dementia, senile dementia, or Down syndrome.
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N(C=1N=C2[C@H](CCCCN2N1)C3=C(F)C(F)=C(F)C=C3)[C@H]4[C@@]5(CN(C[C@]4(CC5)[H])C=6C=C(C)N=CN6)[H]
Molecular Formula
C25H28F3N7
Molecular Weight
483.532
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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