RegisterLogin

PF-06862309

CAT: 0804-HY-138302Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-138302Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PF-06862309 is a PF-06843195 (HY-131972) phosphate ester prodrug. PF-06862309 can be hydrolyzed to PF-06843195 in the presence of alkaline phosphatase. PF-06843195 is a highly selective PI3Kα inhibitor. PF-06862309 can be used for the study of breast cancer with ER+, HER2-, and PIK3CA mutations[1].
CAS Number
[2067281-52-9]
UNSPSC
12352005
Target
Drug Intermediate
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=[P](O)(O)OC[C@@](CN1C(OCC(F)F)=O)(CC1)NC2=NC(N3CCOCC3)=NC(C(C=N4)=CN=C4N)=C2F
Molecular Formula
C20H26F3N8O7P
Molecular Weight
578.44
References & Citations
[1]Hengmiao Cheng, et al. Structure-Based Drug Design and Synthesis of PI3Kα-Selective Inhibitor (PF-06843195) . J Med Chem. 2021 Jan 14;64 (1) :644-661.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-116184PF-05387252
HY-137055PF-3774076
HY-117621PF-04634817
HY-15502-01PF-3635659
HY-117900PF-06250112
HY-169206PF-3166
HY-13810PF-04880594
HY-10867-01PF-622
HY-125789-01PF-04753299
HY-164002PF-303

Alternative Products

CatalogName
T69948-01PF-06862309
MBS579460PF-03084014 (PF-3084014)
OR1103329PF-06827443
MBS3602138-01PF-06447475
MBS3601851-01PF-06282999
MBS3600315-01PF-04418948
MBS3617062-01PF 00356231
MBS3614653-01PF-04745637
MBS3602700-01PF-06651600
MBS3600407-01PF-04620110

Popular Products