Ro-65-3479

CAT: 0804-HY-131292Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-131292Size:1 Each
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Description
Ro-65-3479 is a selective metabotropic glutamate receptor (mGlu2/3) antagonist. Ro-65-3479 blocks glutamate-induced signaling and modulates calcium channel activity. Ro-65-3479 is promising for research of disorders involving glutamatergic dysregulation, such as anxiety, schizophrenia, and neurodegenerative diseases[1].
CAS Number
[259134-85-5]
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
MGluR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C([C@@]1(N)[C@]2([H])[C@@H](C(O)=O)[C@]2([H])C[C@H]1O)O
Molecular Formula
C8H11NO5
Molecular Weight
201.18
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Knoflach F, et al. Pharmacological properties of native metabotropic glutamate receptors in freshly dissociated Golgi cells of the rat cerebellum. Neuropharmacology. 2001;40 (2) :163-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
MGluR2; mGluR3

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