Products for Research Use Only
RegisterLogin

VK4-116

CAT: 0804-HY-123889Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-123889Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
VK4-116 (Compound 19) is a selective Dopamine D3 receptor (D3R) antagonist with a Ki of 6.84 nM.VK4-116 significantly inhibits Oxycodone-induced hyperlocomotion and locomotor sensitization in mouse models. VK4-116 with pretreatment also inhibits the acquisition of Oxycodone-induced conditioned place preference (CPP) in rat models[1].
CAS Number
1982347-43-2
UNSPSC
12352005
Target
Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C1=CC2=C(N1)C=CC=C2)NCCC(CN3CCN(CC3)C4=CC(CC)=CC(Cl)=C4OC)O
Molecular Formula
C26H33ClN4O3
Molecular Weight
485.02
References & Citations
[1]Kumar V, et al. Highly Selective Dopamine D3 Receptor (D3R) Antagonists and Partial Agonists Based on Eticlopride and the D3R Crystal Structure: New Leads for Opioid Dependence Treatment. J Med Chem. 2016 Aug 25;59 (16) :7634-50.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D3 Receptor

Related Products

CatalogName
HY-P3135CPN-116
HY-104064-011A-116
HY-175592-01HEAL-116
HY-168531-01EMU-116
HY-163723EGFR-IN-116
HY-115133ABT-116
HY-155068-01FC-116
HY-116683-01116-9e
HY-10558-01CYC-116
HY-139039-01BSJ-4-116

Alternative Products

CatalogName
GTR19274879-01VK4-116
BA2810-5.11A-116
KAC53336-01TAS-116
PNM-3408-VCPN-116
007247CYC-116
BUP09184-01FC-116
GTR19198917-01116-9e
GTR19195975-01ABT-116
ABC-TC0337HCT-116
MBS132136-01CYC 116

Popular Products