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SNAP8719 (free base)

CAT: 0804-HY-123514Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-123514Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SNAP8719 free base is a selective α1D-adrenoceptor antagonist (pKi = 8.89) . SNAP8719 free base shows affinity for the dopamine D2-, 5-HT1A-, and the human clonal α2a-adrenoceptor, with pKi values of 5.98, 6.47, and [1].
CAS Number
255893-38-0
UNSPSC
12352005
Target
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Smiles
O=C(N([C@H](C)CN1CCN(C2=CC(F)=C(F)C=C2F)CC1)C(C3)=O)CC43CCCC4
Molecular Formula
C22H28F3N3O2
Molecular Weight
423.47
References & Citations
[1]Buckner SA, et al. A-315456: a selective alpha (1D) -adrenoceptor antagonist with minimal dopamine D (2) and 5-HT (1A) receptor affinity. Eur J Pharmacol. 2001 Dec 14;433 (1) :123-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; D2 Receptor; α adrenergic receptor

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