MK-0916

• Description:

  MK-0916 is a HSD1 inhibitor. MK-0916 produces mechanism-based activation of the hypothalamic-pituitary-adrenal axis. MK-0916 can be used in the research of type 2 diabetes and metabolic syndromes[1].

• UNSPSC:

  12352005

• Target:

  11β-HSD

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease; Cardiovascular Disease

• Smiles:

  F[C@@H]1C[C@](C2=NN=C(C3CC3)N2C4CC4)(C5=CC=C(C=C5)Cl)C1

• Molecular Formula:

  C18H19ClFN3

• Molecular Weight:

  331.81

• References & Citations:

  [1]Feig PU, et al. Effects of an 11β-hydroxysteroid dehydrogenase type 1 inhibitor, MK-0916, in patients with type 2 diabetes mellitus and metabolic syndrome. Diabetes Obes Metab. 2011 Jun;13 (6) :498-504.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [633317-53-0]