IM-12 (Standard)

• Description:

  IM-12 (Standard) is the analytical standard of IM-12. This product is intended for research and analytical applications. IM-12 is an inhibitor of GSK-3β, with an IC50 of 53 nM, and also enhances Wnt signalling.

• UNSPSC:

  12352100

• Target:

  GSK-3; Reference Standards; Wnt

• Related Pathways:

  Others; PI3K/Akt/mTOR; Stem Cell/Wnt

• Field of Research:

  Cancer

• Smiles:

  O=C(C(NCCC1=CC=C(F)C=C1)=C2C3=C(C)NC4=C3C=CC=C4)N(C)C2=O

• Molecular Formula:

  C22H20FN3O2

• Molecular Weight:

  377.41

• References & Citations:

  [1]Schmole AC, et al. Novel indolylmaleimide acts as GSK-3beta inhibitor in human neural progenitor cells. Bioorg Med Chem. 2010 Sep 15;18 (18) :6785-95.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [1129669-05-1]