Products for Research Use Only
RegisterLogin

ANA-12 (Standard)

CAT: 0804-HY-12497R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-12497R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ANA-12 (Standard) is the analytical standard of ANA-12. This product is intended for research and analytical applications. ANA-12 is a potent and selective TrkB antagonist with IC50s of 45.6 nM and 41.1 μM for the high and low affinity sites, respectively.
CAS Number
219766-25-3
UNSPSC
12352100
Target
Reference Standards; Trk Receptor
Related Pathways
Neuronal Signaling; Others; Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease
Smiles
O=C(C1=CC2=CC=CC=C2S1)NC3=CC=CC=C3C(NC4C(NCCCC4)=O)=O
Molecular Formula
C22H21N3O3S
Molecular Weight
407.49
References & Citations
[1]Cazorla M, et al. Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice. J Clin Invest. 2011 May;121 (5) :1846-57.|[2]Zhang JC, et al. Comparison of ketamine, 7,8-dihydroxyflavone, and ANA-12 antidepressant effects in the social defeat stress model of depression. Psychopharmacology (Berl) . 2015 Dec;232 (23) :4325-35.|[3]Vassoler FM, et al. Epigenetic inheritance of a cocaine-resistance phenotype. Nat Neurosci. 2013 Jan;16 (1) :42-7.|[4]Fang X, et al. Brain-derived neurotrophic factor-TrkB signaling in the medial prefrontal cortex plays a role in the anhedonia-like phenotype after spared nerve injury. Eur Arch Psychiatry Clin Neurosci. 2018 Jun 7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-12497-01ANA-12
HY-N7195R12-Deoxywithastramonolide (Standard)
HY-12292RIM-12 (Standard)
HY-17499REGFR-IN-12 (Standard)
HY-13734R-01PX-12 (Standard)
HY-19844ANA-975
HY-W403933R12-Ketochenodeoxycholic acid (Standard)
HY-21315RPitavastatin impurity 12 (Standard)
HY-W127329R-0112-Hydroxystearic acid (Standard)
HY-Z6535RLidocaine impurity 12 (Standard)

Alternative Products

CatalogName
SAYP121Reagecon Saybolt +12 Colour Standard
GARD12Reagecon Gardner 12 Colour Standard
PH-BUFF12-500PH 12 Buffer Standard 500mL
MBS5798260(+/-)11(12)-DiHET MaxSpec Standard
GTR19222991(±) 11 (12) -DiHET MaxSpec Standard
MT51350094-250MLMettler-Toledo conductivity standard 12
CON4506Conductivity Standard 12.88ms 500ml
5217Mouse ANA IgG +ve control serum; standard F (10 ug/ml)
KD484915-125PCR Tube 12 Strip - white (Standard)
KD484926-125PCR Tube 12 Strip - clear (Standard)

Popular Products