MK-0448

• Description :

  MK-0448 is a specific Kv1.5 inhibitor used in the research of atrial fibrillation[1].

• UNSPSC :

  12352005

• Target :

  Potassium Channel

• Related Pathways :

  Membrane Transporter/Ion Channel

• Field of Research :

  Cardiovascular Disease

• Purity :

  99.79

• Smiles :

  CS(=O)(NC1=NC([C@H](C2=CC=C(F)C=C2)C(C3=CC=CN=C3)C4=CC=CN=C4)=CC=C1)=O

• Molecular Formula :

  C24H21FN4O2S

• Molecular Weight :

  448.51

• References & Citations :

  [1]Pavri BB, et al. MK-0448, a specific Kv1.5 inhibitor: safety, pharmacokinetics, and pharmacodynamic electrophysiology in experimental animal models and humans. Circ Arrhythm Electrophysiol. 2012 Dec;5 (6) :1193-201.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [875562-81-5]