AZD-8165

• Description :

  AZD-8165 is a highly selective neutral thrombin inhibitor. AZD-8165 is promising for research of cardiovascular diseases such as hypertension and heart failure[1].

• CAS Number :

  [1201686-72-7]

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H373

• Target :

  Thrombin

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=C([C@@H]1CC=NN1C([C@@H](C2=CC=C(F)C=C2)OC(CC)=O)=O)NCC3=CC(Cl)=CC=C3N4N=NN=C4

• Molecular Formula :

  C23H21ClFN7O4

• Molecular Weight :

  513.91

• Precautions :

  P260-P264-P270-P330-P501

• References & Citations :

  [1]Pokhodylo N, et al. The (1H-Tetrazol-1-yl) arenediazonium Salts as Convenient Reagents for Quinones Arylation: Synthesis of 1, 3-Benzoxathiol-2-ones and Naphtho [2, 1-d][1, 3] oxathiol-2-ones Bearing (1H-Tetrazol-1-yl) phenyl Motif[J]. Chemistry, 17 (2) : 304-314.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 1