YM 13650

• Description :

  YM 13650 is an orally active anti-nephritic agent. YM 13650 exhibits dose-dependent preventive and therapeutic effects in both the rat immune complex nephritis model and the mouse spontaneous lupus nephritis model. YM 13650 can inhibit the increase in urinary protein, improve serum cholesterol and urea nitrogen levels, alleviate renal pathological damage, and prolong the survival time of mice. YM 13650 can be used in the research of nephritic diseases[1].

• CAS Number :

  [87545-58-2]

• UNSPSC :

  12352005

• Target :

  Others

• Related Pathways :

  Others

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=C(OC1=CC=CC(C2=CN3C(SC4=CC=CC=C34)=N2)=C1)CC(O)=O

• Molecular Formula :

  C18H12N2O4S

• Molecular Weight :

  352.36

• References & Citations :

  [1]Yamada T, et al. [Effects of YM-13650 on experimental nephritis in rats and mice]. Nihon Yakurigaku Zasshi. 1991 Apr;97 (4) :199-207. Japanese.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported