PX-316

• Description :

  PX-316 is an Akt inhibitor. PX-316 can phosphorylate Akt, but does not inhibit the phosphorylation of PDK1 or PKC. PX-316 uniquely increases the expression of a group of mitochondrial-related genes. PX-316 can be used for the study of colon cancer and breast cancer[1].

• UNSPSC :

  12352211

• Target :

  Akt

• Related Pathways :

  PI3K/Akt/mTOR

• Field of Research :

  Cancer

• Smiles :

  CCCCCCCCCCCCCCCCCCOC[C@@H](OC)COP(O[C@H]1[C@@H]([C@H]([C@@H](C[C@H]1O)O)O)O)(O)=O

• Molecular Formula :

  C28H57O10P

• Molecular Weight :

  584.72

• References & Citations :

  [1]Meuillet EJ, et al. In vivo molecular pharmacology and antitumor activity of the targeted Akt inhibitor PX-316. Oncol Res. 2004;14 (10) :513-27.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Akt

• CAS Number :

  [253440-95-8]