ZK-316

• Description:

  ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50s ranging from 0.99 to 75.1 nM. ZK-316 can be used in the study of HIV[1].

• UNSPSC:

  12352005

• Target:

  HIV; Reverse Transcriptase

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Smiles:

  N#CC1=CC (C ([2H]) ([2H]) [2H]) =C (OC2=C3SC=CC3=NC (NC4CCN (CC4) CC5=CC=C (C=C5) S (=O) (N) =O) =N2) C (C ([2H]) ([2H]) [2H]) =C1

• Molecular Formula:

  C27H22D6N6O3S2

• Molecular Weight:

  554.72

• References & Citations:

  [1]Zhang K, et al. Deuteration Strategy-Inspired Design of Novel Diarylpyrimidine Derivatives as Potent Non-Nucleoside Reverse Transcriptase Inhibitors Featuring Improved Efficacy, Selectivity, and Druggability. J Med Chem. 2025 Apr 24;68 (8) :8564-8577.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  3027894-30-7