TA-316

CAT: 0804-HY-112486-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-112486-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TA-3166 (Megakaryocytes/platelets inducing agent) is a novel chemically synthesized c-MPL agonist (CMA) and thrombopoietin (TPO) receptor agonist. TA-316 enhances ex vivo platelet generation from human-induced pluripotent stem (iPS) cells[1][2].
CAS Number
[1429321-13-0]
Product Name Alternative
Megakaryocytes/platelets inducing agent
UNSPSC
12352005
Hazard Statement
H303, H315, H319, H335
Target
Cyclin G-associated Kinase (GAK)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neurodegeneration
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Megakaryocytes-platelets_inducing_agent.html
Purity
99.50
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=C(C(NCC2=CC=C(C(NCCO)=O)C=C2)=O)S1)N/N=C(C3=CSC(C4=CC=C(Br)C=C4)=C3O)\C
Molecular Formula
C28H25BrN4O5S2
Molecular Weight
641.56
Precautions
H303, H315, H319, H335
References & Citations
[1]METHOD FOR PRODUCING MEGAKARYOCYTES AND/OR PLATELETS FROM PLURIPOTENT STEM CELLS.WO2013051625A1.|[2]Aihara A, et al. Novel TPO receptor agonist TA-316 contributes to platelet biogenesis from human iPS cells. Blood Adv. 2017;1 (7) :468-476. Published 2017 Feb 28.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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