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PX-316

CAT: 0931-T69589-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T69589-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
253440-95-8
Target
Others
Related Pathways
Others
Bioactivity
PX-316 is a AKT inhibior. PX-316, when administered intraperitoneally to mice at 150 mg/kg, inhibits Akt activation in HT-29 human tumor xenografts up to 78% at 10 h with recovery to 34% at 48 h. PX-316 has antitumor activity against early human MCF-7 breast cancer and HT-29 colon cancer xenografts in mice. PX-316 formulated in 20% hydroxypropyl-beta-cyclodextrin for intravenous administration is well tolerated in mice and rats with no hemolysis and no hematological toxicity. Thus, PX-316 is the lead compound of a new class of potential agents that inhibit Akt survival signaling.
Smiles
O(P(OC[C@@H](COCCCCCCCCCCCCCCCCCC)OC)(=O)O)[C@H]1[C@H](O)[C@@H](O)[C@H](O)C[C@H]1O
Molecular Formula
C28H57O10P
Molecular Weight
584.72
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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