DS-1040

CAT: 0804-HY-117745Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-117745Size:1 Each
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Description
DS-1040 is a low-molecular-weight imidazole derivative. DS-1040 is an inhibitor of the activated thrombin-activatable fibrinolysis (TAFIa) . DS-1040 can promote fibrinolysis through suppressing TAFIa activity. DS-1040 can be studied in thrombolytic disease research[1][2].
CAS Number
[1335138-62-9]
UNSPSC
12352005
Target
Thrombin
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
C[C@H]1CC[C@H](N2C=NC(C[C@@H](C(O)=O)CCCN)=C2)CC1
Molecular Formula
C16H27N3O2
Molecular Weight
293.40
References & Citations
[1]Zhou, J., et al., (2017) . A first-in-human study of DS-1040, an inhibitor of the activated form of thrombin-activatable fibrinolysis inhibitor, in healthy subjects. Journal of thrombosis and haemostasis : JTH, 15 (5), 961-971. |[2]Zhou, J., et al., (2019) . First-in-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of an Oral Formulation of DS-1040, an Inhibitor of the Activated Form of Thrombin-Activatable Fibrinolysis Inhibitor, in Healthy Subjects. Journal of clinical pharmacology, 59 (12), 1669-1677.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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