PPI-1040

• Description :

  PPI-1040 is a synthetic PlsEtn, a precursor of plasmalogens. PPI-1040 is an orally available plasmalogen analog that increases plasmalogen in several peripheral tissues of Pex7 low allele mice. PPI-1040 has the potential to replace deficient plasmalogen and inhibit chondrodysplasia punctata (RCDP) .

• UNSPSC :

  12352005

• Target :

  Drug Derivative

• Related Pathways :

  Others

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Smiles :

  CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(OC(CO/C=C\CCCCCCCCCCCCCC)COP1(NCCO1)=O)=O

• Molecular Formula :

  C43H72NO6P

• Molecular Weight :

  730.01

• References & Citations :

  [1]Fallatah W, et al. Oral administration of a synthetic vinyl-ether plasmalogen normalizes open field activity in a mouse model of rhizomelic chondrodysplasia punctata. Dis Model Mech. 2020 Jan 24;13 (1) :dmm042499.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1436673-69-6]