DS-3801b

• Description:

  DS-3801b is a potent and non-macrolide agonist of GPR38. DS-3801b is expected to be novel gastrointestinal prokinetic agents for the research of functional gastrointestinal disorders such as gastroparesis and chronic constipation[1].

• UNSPSC:

  12352005

• Target:

  Motilin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/ds-3801b.html

• Purity:

  99.18

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C([C@H]1CC[C@H](OC2=CC=CC(CO)=C2)CC1)N(C)C3=CC=C(CN4C[C@H](C)NCC4)C(C)=C3

• Molecular Formula:

  C28H39N3O3

• Molecular Weight:

  465.63

• References & Citations:

  [1]Toda N, et al. Discovery of DS-3801b, a non-macrolide GPR38 agonist with N-methylanilide structure. Bioorg Med Chem Lett. 2022;59:128554.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1369412-66-7]