Bunitrolol (hydrochloride)

CAT: 0804-HY-116957Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-116957Size:1 Each
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Description
Bunitrolol hydrochloride is an orally active β-adrenergic blocker that has a high affinity for β-adrenergic receptors. Bunitrolol hydrochloride exerts significant β-receptor antagonist activity and has weak α1-blocking activity. Bunitrolol hydrochloride is mainly used in the study of cardiovascular diseases such as hypertension and angina pectoris, and is also used in placental transport research[1][2][3].
CAS Number
[29876-08-2]
UNSPSC
12352005
Hazard Statement
H302+H312+H332-H315-H319-H335
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cardiovascular Disease
Smiles
N#CC1=CC=CC=C1OCC(CNC(C)(C)C)O.Cl
Molecular Formula
C14H21ClN2O2
Molecular Weight
284.78
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Tsuchihashi H, et al. Effects of bunitrolol on adrenergic and serotonergic receptors. Jpn J Pharmacol. 1987 Nov;45 (3) :349-56.|[2]Hasegawa Y, et al. Chronic effects of bunitrolol and pindolol on blood pressure, heart rate, vascular lesions, and plasma renin activity in hypertensive rats. Jpn J Pharmacol. 1982 Aug;32 (4) :742-5. |[3]Van Petten G R, et al. Chronic preparation of the pregnant ewe and fetus for pharmacological research: the placental transfer and fetal effects of bunitrolol. Journal of Pharmacological Methods, 1978, 1 (1) : 45-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor

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