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BMS-856

CAT: 0804-HY-112744Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-112744Size:1 Each
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Description
BMS-856 is a 17β-HSD3 inhibitor. BMS-856 inhibits enzymatic activity of 17β-HSD3, with IC50s of 60 and 300 nM respectively in the enzyme and whole cell assays[1].
CAS Number
863382-83-6
UNSPSC
12352005
Target
17β-HSD
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(C1=CC=C(C(Cl)=C1)O)NC2=CC=C(C=C2C(NCCC3=C(OC)C=CC=C3)=O)OC4=CC=CC=C4
Molecular Formula
C29H25ClN2O5
Molecular Weight
516.97
References & Citations
[1]Day JM, et al. Design and validation of specific inhibitors of 17beta-hydroxysteroid dehydrogenases for therapeutic application in breast and prostate cancer, and in endometriosis. Endocr Relat Cancer. 2008 Sep;15 (3) :665-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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