CGP 31523A

• Description:

  CGP 31523A is a broad-spectrum aminothiazole cephalosporin. CGP 31523A exhibits potent inhibitory effects on Enterobacteriaceae, Neisseria, Haemophilus influenzae, and Streptococcus (except Enterococcus faecalis), among others. CGP 31523A can be hydrolyzed by the common Escherichia coli type Ic β-lactamase, but is stable against the Ia type enzyme. CGP 31523A is neither an effective β-lactamase inhibitor nor does it induce the production of β-lactamase. CGP 31523A can be used for studying infections caused by Gram-negative bacteria (including drug-resistant strains) [1].

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  OC(C1=C(CSC2=CN=NS2)CS[C@@]([C@@H]3NC([C@H](C4=CSC(N)=N4)NC=O)=O)([H])N1C3=O)=O

• Molecular Formula:

  C16H15N7O5S4

• Molecular Weight:

  513.59

• References & Citations:

  [1]Chin NX, Neu HC. Comparative in vitro activity and beta-lactamase stability of CGP 31523A, a new aminothiazolyl cephalosporin. Chemioterapia. 1986 Apr;5 (2) :92-100.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [94714-78-0]