Pifithrin-μ (Standard)

• Description :

  Pifithrin-μ (Standard) is the analytical standard of Pifithrin-μ. This product is intended for research and analytical applications. Pifithrin-μ is an inhibitor of p53 and HSP70, with antitumor and neuroprotective activity.

• UNSPSC :

  12352100

• Target :

  Autophagy; HSP; MDM-2/p53; Reference Standards

• Related Pathways :

  Apoptosis; Autophagy; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others

• Field of Research :

  Cancer; Neurological Disease

• Smiles :

  O=S(C#CC1=CC=CC=C1)(N)=O

• Molecular Formula :

  C8H7NO2S

• Molecular Weight :

  181.21

• References & Citations :

  [1]Strom E, et al. Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. Nat Chem Biol. 2006 Sep;2 (9) :474-9. Epub 2006 Jul 23.|[2]Zhou Y, et al. Pifithrin-μ is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70. Oncol Rep. 2017 Jan;37 (1) :313-322.|[3]Glas M, et al. Neuroprotection with the P53-Inhibitor Pifithrin-μ after Cardiac Arrest in a Rodent Model. Shock. 2018 Feb;49 (2) :229-234.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [64984-31-2]