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Pifithrin-μ (Standard)

CAT: 0804-HY-10940R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-10940R-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pifithrin-μ (Standard) is the analytical standard of Pifithrin-μ. This product is intended for research and analytical applications. Pifithrin-μ is an inhibitor of p53 and HSP70, with antitumor and neuroprotective activity.
CAS Number
[64984-31-2]
UNSPSC
12352100
Target
Autophagy; HSP; MDM-2/p53; Reference Standards
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Neurological Disease
Smiles
O=S(C#CC1=CC=CC=C1)(N)=O
Molecular Formula
C8H7NO2S
Molecular Weight
181.21
References & Citations
[1]Strom E, et al. Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation. Nat Chem Biol. 2006 Sep;2 (9) :474-9. Epub 2006 Jul 23.|[2]Zhou Y, et al. Pifithrin-μ is efficacious against non-small cell lung cancer via inhibition of heat shock protein 70. Oncol Rep. 2017 Jan;37 (1) :313-322.|[3]Glas M, et al. Neuroprotection with the P53-Inhibitor Pifithrin-μ after Cardiac Arrest in a Rodent Model. Shock. 2018 Feb;49 (2) :229-234.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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