SC-57461

• Description:

  SC-57461 is a potent, selective, and orally effective LTA4 hydrolase (Ki = 23 nM and 27 nM) inhibitor. SC-57461 can significantly inhibit edema. SC-57461 is commonly used in the study of inflammatory skin conditions[1].

• UNSPSC:

  12352005

• Target:

  Aminopeptidase

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C(CCN(CCCOC1=CC=C(CC2=CC=CC=C2)C=C1)C)O

• Molecular Formula:

  C20H25NO3

• Molecular Weight:

  327.42

• References & Citations:

  [1]Kachur J F, et al. Pharmacological Characterization of SC-57461A (3-[Methyl [3-[4- (phenylmethyl) phenoxy] propyl] amino] propanoic Acid HCl), a Potent and Selective Inhibitor of Leukotriene A4Hydrolase II: In Vivo Studies[J]. The Journal of pharmacology and experimental therapeutics, 2002, 300 (2) : 583-587.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [179022-08-3]