NDC 1308

• Description :

  NDC 1308 is an estradiol analogue. NDC 1308 can bind estrogen receptor beta and inhibit cancer cell proliferation by blocking chromosome replication. NDC 1308 can be used for the research of cancer, such as breast cancer[1].

• UNSPSC :

  12352005

• Target :

  DNA/RNA Synthesis; Estrogen Receptor/ERR

• Related Pathways :

  Cell Cycle/DNA Damage; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Cancer

• Smiles :

  C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@](C4=CC=C(O)C=C4[C@H](CCCCCCOC)C3)([H])CC1

• Molecular Formula :

  C25H38O3

• Molecular Weight :

  386.57

• References & Citations :

  [1]Weitman S D, et al. A steroid-based drug that binds estrogen receptor beta can inhibit cancer cell proliferation by blocking chromosome replication[J]. Cancer Research, 2010, 70 (8_Supplement) : 1721-1721.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1227511-09-2]