(±) -CPSI-1306

• Description :

  (±) -CPSI-1306 is an orally available antagonist of macrophage migration inhibitory factor (MIF) .

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Macrophage migration inhibitory factor (MIF)

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Metabolic Disease; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/__plusmn__-CPSI-1306.html

• Purity :

  99.64

• Solubility :

  DMSO : 6 mg/mL (ultrasonic)

• Smiles :

  FC1=C(C=CC(F)=C1)C2=NOC(CC(N3CCOCC3)=O)C2

• Molecular Formula :

  C15H16F2N2O3

• Molecular Weight :

  310.30

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Sanchez-Zamora Y, et al. Macrophage migration inhibitory factor is a therapeutic target in treatment of non-insulin-dependent diabetes mellitus. FASEB J. 2010 Jul;24 (7) :2583-90.|[2]Nagarajan P, et al. MIF antagonist (CPSI-1306) protects against UVB-induced squamous cell carcinoma. Mol Cancer Res. 2014 Sep;12 (9) :1292-302.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1309793-47-2]