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GR 250495X

CAT: 0804-HY-106983Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106983Size:1 Each
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Description
GR 250495X is an inhaled glucocorticoid receptor agonist. GR 250495X is designed as a antedrug, which takes effect locally in the lungs but is rapidly metabolized and inactivated in the bloodstream after entering the systemic circulation, thereby minimizing systemic side effects. GR 250495X can be used in asthma research[1].
CAS Number
192057-17-3
UNSPSC
12352005
Target
Glucocorticoid Receptor
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(OCC1)[C@H]1SC([C@]23[C@@]4([C@@]([C@@]5([H])[C@]([C@H](C4)O)([C@@]6(C([C@H](C5)F)=CC(CC6)=O)C)F)([H])C[C@@]2([H])O[C@H](O3)CCC)C)=O
Molecular Formula
C28H36F2O7S
Molecular Weight
554.64
References & Citations
[1]Sharp MJ, et al. Synthesis of Steroid'Antedrugs' for Evaluation as Safe Treatments for Asthma: Practical Synthesis of the Inhaled Steroid GR250495X.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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