NIP-121

• Description :

  NIP-121 is a new type of potassium channel opener. NIP-121 significantly reduces mean pulmonary artery pressure and total pulmonary resistance through vasodilation. NIP-121 can be used for research on pulmonary arterial hypertension[1].

• UNSPSC :

  12352005

• Target :

  Potassium Channel

• Related Pathways :

  Membrane Transporter/Ion Channel

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O[C@@H]1[C@@H](N2C(CCCC2)=O)C3=CC4=NON=C4C=C3OC1(C)C

• Molecular Formula :

  C16H19N3O4

• Molecular Weight :

  317.34

• References & Citations :

  [1] Tanaka H, et al. Cardioprotective effects of NIP-121, a novel ATP-sensitive potassium channel opener, during ischemia and reperfusion in coronary perfused guinea pig myocardium. J Cardiovasc Pharmacol. 1996 May;27 (5) :695-701.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [135244-62-1]