NIP-22c

• Description :

  NIP-22c is a novel coronavirus 3CLpro inhibitor. The EC50 for Verona, Calu3, Caco2 and HBTEC-ALI were 4.6, 1.1, 0.1 and 0.6 μM, respectively. NIP-22c has antiviral activity[1].

• UNSPSC :

  12352005

• Target :

  SARS-CoV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/nip-22c.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N[C@@H](CC(C)C)C(N[C@@H](C[C@@H]1CCCNC1=O)C=O)=O)[C@@H](NC(C2=NOC(C)=C2)=O)CC3=CC=CC4=C3C=CC=C4

• Molecular Formula :

  C32H39N5O6

• Molecular Weight :

  589.68

• References & Citations :

  [1]Amblard F, et al. Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease. Eur J Med Chem. 2024 Feb 24;268:116263.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2309384-85-6]