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NIP-22c

CAT:
804-HY-162313
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
NIP-22c - image 1

NIP-22c

  • CAS Number: 2309384-85-6
  • UNSPSC Description: NIP-22c is a novel coronavirus 3CLpro inhibitor. The EC50 for Verona, Calu3, Caco2 and HBTEC-ALI were 4.6, 1.1, 0.1 and 0.6 μM, respectively. NIP-22c has antiviral activity[1].
  • Target Antigen: SARS-CoV
  • Type: Reference compound
  • Related Pathways: Anti-infection
  • Applications: COVID-19-anti-virus
  • Field of Research: Infection
  • Assay Protocol: https://www.medchemexpress.com/nip-22c.html
  • Solubility: 10 mM in DMSO
  • Smiles: O=C(N[C@@H](CC(C)C)C(N[C@@H](C[C@@H]1CCCNC1=O)C=O)=O)[C@@H](NC(C2=NOC(C)=C2)=O)CC3=CC=CC4=C3C=CC=C4
  • Molecular Weight: 589.68
  • References & Citations: [1]Amblard F, et al. Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease. Eur J Med Chem. 2024 Feb 24;268:116263.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported