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NIP-22c

CAT: 0804-HY-162313Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162313Size:1 Each
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Description
NIP-22c is a novel coronavirus 3CLpro inhibitor. The EC50 for Verona, Calu3, Caco2 and HBTEC-ALI were 4.6, 1.1, 0.1 and 0.6 μM, respectively. NIP-22c has antiviral activity[1].
CAS Number
2309384-85-6
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nip-22c.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC(C)C)C(N[C@@H](C[C@@H]1CCCNC1=O)C=O)=O)[C@@H](NC(C2=NOC(C)=C2)=O)CC3=CC=CC4=C3C=CC=C4
Molecular Formula
C32H39N5O6
Molecular Weight
589.68
References & Citations
[1]Amblard F, et al. Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease. Eur J Med Chem. 2024 Feb 24;268:116263.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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