NIP-22c

• Description:

  NIP-22c is a novel coronavirus 3CLpro inhibitor. The EC50 for Verona, Calu3, Caco2 and HBTEC-ALI were 4.6, 1.1, 0.1 and 0.6 μM, respectively. NIP-22c has antiviral activity[1].

• UNSPSC:

  12352005

• Target:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/nip-22c.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C (N[C@@H] (CC (C) C) C (N[C@@H] (C[C@@H]1CCCNC1=O) C=O) =O) [C@@H] (NC (C2=NOC (C) =C2) =O) CC3=CC=CC4=C3C=CC=C4

• Molecular Formula:

  C32H39N5O6

• Molecular Weight:

  589.68

• References & Citations:

  [1]Amblard F, et al. Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease. Eur J Med Chem. 2024 Feb 24;268:116263.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2309384-85-6