UH-NIP-16

• UNSPSC Description:

  UH-NIP-16 exhibits antimicrobial activity against Mycobacterium tuberculosis, with MIC50 of 1.86 and 3.05 μM, for pathogenic mycobacterial strains H37Rv and CDC1551. UH-NIP-16 synergizes with Streptomycin (HY-B1906), Isoniazid (HY-B0329), Ethambutol (HY-B0535) and Bedaquiline (HY-14881), potentiates their anti-tuberculosis activities[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/uh-nip-16.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N/N=C\C1=CC2=CC(OC)=CC=C2N=C1Cl)C3=CC=NC=C3

• Molecular Weight:

  340.76

• References & Citations:

  [1]Vadankula GR, et al., Confronting Tuberculosis: A Synthetic Quinoline-Isonicotinic Acid Hydrazide Hybrid Compound as a Potent Lead Molecule Against Mycobacterium tuberculosis. ACS Infect Dis. 2024 May 8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported