ABT-072 (Standard)

CAT: 0804-HY-101634RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-101634RSize:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
ABT-072 (Standard) is the analytical standard of ABT-072 (HY-101634) . This product is intended for research and analytical applications. ABT-072 is an orally active and potent non-nucleoside HCV NS5B polymerase inhibitor (HCV GT1a EC50=1 nM; HCV GT1b EC50=0.3 nM) [1][2][3].
CAS Number
[1132936-00-5]
Target
HCV; Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
CS(=O)(NC1=CC=C(/C=C/C2=CC(N(C(N3)=O)C=CC3=O)=CC(C(C)(C)C)=C2OC)C=C1)=O
Molecular Formula
C24H27N3O5S
Molecular Weight
469.55
References & Citations
[1]Lawitz E, et al. A phase 2a trial of 12-week interferon-free therapy with two direct-acting antivirals (ABT-450/r, ABT-072) and ribavirin in IL28B C/C patients with chronic hepatitis C genotype 1. J Hepatol. 2013;59 (1) :18-23.|[2]Shi Y, et al. Assessing Supersaturation and Its Impact on In Vivo Bioavailability of a Low-Solubility Compound ABT-072 With a Dual pH, Two-Phase Dissolution Method. J Pharm Sci. 2016;105 (9) :2886-2895.|[3]Randolph JT, et al. Synthesis and Biological Characterization of Aryl Uracil Inhibitors of Hepatitis C Virus NS5B Polymerase: Discovery of ABT-072, a trans-Stilbene Analog with Good Oral Bioavailability. J Med Chem. 2018;61 (3) :1153-1163.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-101634ARABT-072 (potassium trihydrate) (Standard)
HY-101634-01ABT-072
HY-101634A-01ABT-072 (potassium trihydrate)
HY-13270R-01ABT-751 (Standard)
HY-178738GC-072
HY-164476-01ES-072
HY-172175HYS-072
HY-168995BAR-072
HY-15197-01ABT-046
HY-19483ABT-670

Alternative Products

CatalogName
M10465-01ABT-072
A20177-100ABT-072 100mg
A20177-1ABT-072 1mg
A20177-25ABT-072 25mg
A20177-5ABT-072 5mg
A20177-10ABT-072 10mg
A20177-50ABT-072 50mg
MBS5799148-01ABT-072 potassium trihydrate
596357JWH 072
MF-0113708-01HYS-072

Popular Products