BAR-072

• Description :

  BAR-072 is a small-molecule inhibitor targeting TraE, with a KD of 2.7 µM. It significantly inhibits the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 shows promise as a candidate compound for blocking the spread of bacterial resistance genes and holds potential for research in infectious disease and antimicrobial resistance control[1].

• UNSPSC :

  12352211

• Target :

  Bacterial

• Related Pathways :

  Anti-infection

• Field of Research :

  Infection

• Smiles :

  O=C(C1=C(C=CC(O)=C1)O)N/N=C/C2=CC=C(O2)C3=CC=CC=C3[N+]([O-])=O

• Molecular Formula :

  C18H13N3O6

• Molecular Weight :

  367.31

• References & Citations :

  [1]Casu B, et al. Structural Analysis and Inhibition of TraE from the pKM101 Type IV Secretion System. J Biol Chem. 2016 Nov 4;291 (45) :23817-23829.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [2068867-65-0]