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ABT-670

CAT: 0804-HY-19483Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19483Size:1 Each
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Description
ABT-670 is a selective, oral bioavailable agonist of dopamine D4 receptor, with EC50 of 89 nM, 160 nM, and 93 nM for human D4, ferret D4, and rat D4, respectively.
CAS Number
630119-43-6
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ABT-670.html
Solubility
10 mM in DMSO
Smiles
O=C(NCN1CCC(C2=CC=CC=[N+]2[O-])CC1)C3=CC=CC(C)=C3
Molecular Formula
C19H23N3O2
Molecular Weight
325.40
References & Citations
[1]Patel MV, et al. Discovery of 3-methyl-N- (1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl) benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction. J Med Chem. 2006 Dec 14;49 (25) :7450-65.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D4 Receptor

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