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AZD-1236

CAT: 0804-HY-101276Size: 1 EachDry Ice: NoHazardous: No
CAT#: HY-101276Size: 1 Each
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZD1236 is a potent and reversible inhibitor of human MMP-9 and MMP-12.
CAS Number
[459814-89-2]
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
MMP
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
C[C@@]1(NC(NC1=O)=O)CS(=O)(N2CCC(CC2)OC3=CC=C(C=N3)Cl)=O
Molecular Formula
C15H19ClN4O5S
Molecular Weight
402.85
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Magnussen H, Watz H, Kirsten A, Wang M, Wray H, Samuelsson V, Mo J, Kay R. Safety and tolerability of an oral MMP-9 and -12 inhibitor, AZD1236, in patients with moderate-to-severe COPD: a randomised controlled 6-week trial. Pulm Pharmacol Ther. 2011 Oct;24 (5) :563-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
MMP-12; MMP-9

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