UCM 608 (Standard)
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UCM 608 (Standard)
Description:
UCM 608 (Standard) is the analytical standard of UCM 608 (HY-101074) . This product is intended for research and analytical applications. UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].Target:
Melatonin Receptor; Reference StandardsRelated Pathways:
GPCR/G Protein; Neuronal Signaling; OthersField of Research:
Cancer; Inflammation/Immunology; Neurological DiseaseSmiles:
CC(NCCC1=C(C2=CC=CC=C2)NC3=C1C=C(OC)C=C3)=OMolecular Formula:
C19H20N2O2Molecular Weight:
308.37References & Citations:
[1] Radogna F, et al. Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes. Toxicol Appl Pharmacol. 2009;239 (1) :37-45.|[2]Mor, M., et al. Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands. Bioorganic & Medicinal Chemistry, 9 (4), 1045–1057.Shipping Conditions:
Room temperatureScientific Category:
Reference StandardsCAS Number:
[151889-03-1]
