C 87 (Standard)

CAT: 0804-HY-100735RSize: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-100735RSize:1 Each

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Description

C 87 (Standard) is the analytical standard of C 87. This product is intended for research and analytical applications. C 87 is a novel small-molecule TNFα inhibitor; potently inhibits TNFα-induced cytotoxicity with an IC50 of 8.73 μM.

CAS Number

332420-90-3

Target

Reference Standards; TNF Receptor

Related Pathways

Apoptosis; Others

Field of Research

Inflammation/Immunology

Smiles

O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=CC=C(Cl)C([N+]([O-])=O)=C5

Molecular Formula

C24H15ClN6O3S

Molecular Weight

502.93

References & Citations

[1]Ma L, et al. A novel small-molecule tumor necrosis factor α inhibitor attenuates inflammation in a hepatitis mouse model. J Biol Chem. 2014 May 2;289 (18) :12457-66.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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C 87 (Standard)

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