C 87

CAT: 0804-HY-100735-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100735-01Size:5 mg
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Description
C 87 is a novel small-molecule TNFα inhibitor; potently inhibits TNFα-induced cytotoxicity with an IC50 of 8.73 μM.
CAS Number
[332420-90-3]
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/C-87.html
Purity
98.06
Solubility
DMSO : 5.05 mg/mL (ultrasonic)
Smiles
O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=CC=C(Cl)C([N+]([O-])=O)=C5
Molecular Formula
C24H15ClN6O3S
Molecular Weight
502.93
References & Citations
[1]Ma L, et al. A novel small-molecule tumor necrosis factor α inhibitor attenuates inflammation in a hepatitis mouse model. J Biol Chem. 2014 May 2;289 (18) :12457-66.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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