XMD8-87

CAT: 0804-HY-15811-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15811-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XMD8-87 is a potent TNK2 inhibitor with IC50 values of 38 and 113 nM for the D163E and R806Q mutations, respectively.
CAS Number
[1234480-46-6]
Product Name Alternative
ACK1-B19
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Tyrosinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/XMD8-87.html
Purity
99.57
Solubility
DMSO : ≥ 26 mg/mL
Smiles
O=C1C2=CC=CC=C2N(C)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4OC)=NC=C3N1
Molecular Formula
C24H27N7O2
Molecular Weight
445.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Maxson JE, et al. Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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