Cyclo (CRVIIF)

• Target:

  HIF/HIF Prolyl-Hydroxylase

• Related Pathways:

  Chromatin/Epigenetic|||Metabolism

• Bioactivity:

  Cyclo CRVIIF is a dual inhibitor of hypoxia-inducible factors HIF1 and HIF2. It disrupts the interaction between HIF1-?, HIF2-?, and HIF1-?, with dissociation constants (KD) for the PAS-B domains of HIF1-? and HIF2-? measured at 65 and 123 ?M, respectively.

• Molecular Formula:

  C35H57N9O6S

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C